Neurofeedback might have clinical potential for patients with non-anxious major depressive disorder

“The study, published in Psychological Medicine, examined a neurofeedback intervention targeting self-blaming biases in major depressive disorder

“Excessive self-blame is an important symptom and cause of depression and distinguishes depression from healthy bereavement, as Sigmund Freud pointed out,” said study author Roland Zahn, a professor at King’s College London and honorary consultant psychiatrist at Maudsley Hospital.

“Together with my colleague Jorge Moll from the D’Or Institute for Research and Education in Rio de Janeiro, my research group has started to identify the brain circuits that are important for overgeneralized self-blame in depression (e.g. ‘feeling like a total failure’ or ‘feeling guilty for everything’ or ‘loathing oneself’).”

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